Great gameplay.
Great story.
Great music.
Great humor.
Just beat "Crushing" mode (and got 100%) the other day. I love this game.
One of the most interesting things about Uncharted is the enemy AI.
I dont play much shooters, but these guys get behind cover, pop out from it in everyway possible (above, side, roll, crouch, lie down) and they can even flank you. Which is crazy.
The puzzle/platform elements even flow well with the shooting.
The graphics are pretty damn amazing, in the levels that have jungle in it, it looks like a real jungle. It also has water; streams, rivers, waterfalls, oceans. Which is flawless. The main character's clothes even get wet, and eventually dry out over time.
The lighting is amazing also. Not just in cutscenes, but in regular gameplay, you have sunlight, filtering through the canopy and hitting landscape and the characters.
The story is awesome, with lots of twists along the way. Naughty Dog used motion capture for the game, which really shows in the character's natural movements.
The dialouge is funny, and NEVER cheezy. It also has great characters, my favourite being Drake's rival, Eddie.

One of the best things about this game, was when you died, you didn't think "arg not again, so annoying",
You thought "Ha! you sneaky so and so, i'll getcha next time!"
Also, like in Ratchet & Clank, they are skill points to get

ND calls them "Medal Points"
Just as fun and challenging as in R&C, they unlock bonuses.
The bonuses for Uncharted, are the best bonuses I have ever seen in a game.
There is TONS of concept and enviroment art. I havent even looked through them all yet. (At the very least 100 great quality pieces)
As well as art, Medal points unlock cheats. These include:
Skins (for Drake and enemies), weapon select, fast motion, slow motion, and even super slow motion. Oh, and unlimited ammo and one shot kills

Uncharted is the best video game I have ever played. Ever.
If you have a PS3, buy this game.
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